Susceptibility of Propionibacterium acnes clinical isolates to 22 antimicrobial agents.

نویسندگان

  • G A Denys
  • R C Jerris
  • J M Swenson
  • C Thornsberry
چکیده

Susceptibilities of 104 Propionibacterium acnes isolates to each of 22 antimicrobial agents was evaluated by broth microdilution. These isolates were susceptible to all of the test agents except metronidazole. N-Formimidoyl thienamycin, a penem coded Sch 29482, and penicillin ranked first, second, and third, respectively, in activity and were significantly more active than other penicillins, cephalosporins, tetracyclines, clindamycin, or chloramphenicol.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Determination of antibiotic susceptibility and Minimum Inhibitory Concentration (MIC) of the Propionibacterium acnes to the prevalent antibiotics in the treatment of Acne vulgaris

ABSTRACTPropionibacterium acnes is propounded as one of the significant factors in occurrence of acne. Today, due to development of the antibiotic resistance, most of the acne treatments are faced with failure. In order to determine the antibiotic resistance of the P.acnes strains isolated from the patients with acne, this research has been carried out. 70 samples collected using microbial cult...

متن کامل

Formation of Propionibacterium acnes biofilms on orthopaedic biomaterials and their susceptibility to antimicrobials.

Failure to treat and eradicate prosthetic hip infection with systemic antibiotic regimens is usually due to the fact that the infection is associated with biofilm formation and that bacterial cells growing within a biofilm exhibit increased resistance to antimicrobial agents. In this in vitro study, we investigated the susceptibility of prosthetic hip Propionibacterium acnes and Staphylococcus ...

متن کامل

Comparative in vitro activities of retapamulin (SB-275833) against 141 clinical isolates of Propionibacterium spp., including 117 P. acnes isolates.

Using the NCCLS agar dilution method, we studied the in vitro activity of retapamulin (SB-275833) against 141 clinical isolates of Propionibacterium species, including seven multiresistant strains, and found retapamulin to be the most active agent among those tested with MICs of < or = 1 microg/ml against all isolates.

متن کامل

Antimicrobial susceptibility of one thousand bacterial isolates to five antibacterial agents commonly used in the Iranian poultry industry

BACKGROUNDS: Different susceptibility rates of pathogenic bacteria to antimicrobial agents are considered major factors in the choice of drugs and the success of treatments. Concerns have been raised regarding the emergence of antimicrobial resistance among pathogenic bacteria that may result in unpredictable antimicrobial susceptibilities and therapy failure. OBJECTIVES: The purpose of this in...

متن کامل

Susceptibilities of Propionibacterium acnes ophthalmic isolates to moxifloxacin.

Propionibacterium acnes has become an important pathogen in nosocomial infection, including endophthalmitis. The treatment of endophthalmitis presents many diagnostic and therapeutic challenges. Although P. acnes has demonstrated in vitro susceptibilities to many beta-lactam agents, clindamycin, and macrolides, intravitreal treatment success in patients has been inconsistent. While quinolones a...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 23 2  شماره 

صفحات  -

تاریخ انتشار 1983